Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 20-ethyl-6,16-dimethoxy-4-(methoxymethyl)-(1a,6a,14a,16ß)-aconitane-1,8,14-triol
Purity: ≥98%
Formula Markup: C24H39NO6
Formula Weight: 437.5696
CAS Number: 466-26-2
Notes: Bullatine B is a diterpene alkaloid that has been found in Aconitum and has diverse biological activities.{58999,58998} It inhibits voltage-gated sodium channel 1.7 (Nav1.7) in HEK293 cells expressing the human channel (IC50 = 25.8 nM) and scavenges DPPH (Item No. 14805) radicals by 65.3% at 1 mM. Bullatine B (10 mg/kg) increases the mechanical pain threshold in the von Frey test in streptozotocin-induced diabetic, but not non-diabetic, mice.{58999}