Shelf life (days): 1460.0
Formulation: A solid
Formal Name: N-[[4-(1,1-dimethylethyl)phenyl]methyl]-N-(methyl-13C-d3)-1-naphthalenemethanamine, monohydrochloride
Purity: ≥99% deuterated forms (d1-d3)
Formula Markup: C22[13C]H24D3N / HCl
Formula Weight: 357.9
CAS Number: 2909036-24-2
Notes: Butenafine-13C-d3 is intended for use as an internal standard for the quantification of butenafine (Item No. 23797) by GC- or LC-MS. Butenafine is a benzylamine antifungal agent that has broad-spectrum activity against 87 strains of dermatophytes (MICs = 0.0015-0.05 µg/ml), 15 strains of Aspergillus (MICs = 0.025-0.78 µg/ml), 4 strains of Cryptococcus (MICs = 0.78-1.56 µg/ml), and 67 strains of Candida (MICs = 3.13 to >100 µg/ml).{38473} It acts by inhibiting squalene epoxidase.{38472} Butenafine (50 µM) inhibits the synthesis of ergosterol (Item No. 19850), a sterol in the cell membranes of fungi. Formulations containing butenafine have been used in the treatment of tinea pedis, tinea corporis, and tinea cruris.
Deutsch
English
