Product Description: Calcipotriol (Standard) is the analytical standard of Calcipotriol. This product is intended for research and analytical applications. Calcipotriol is a synthetic VitD3 analogue with a high affinity for the vitamin D receptor.
Formula: C27H40O3
References: [1]Sakabe JI, et al. Calcipotriol Increases hCAP18 mRNA Expression but Inhibits Extracellular LL37 Peptide Production in IL-17/IL-22-stimulated Normal Human Epidermal Keratinocytes. Acta Derm Venereol. 2014 Sep;94(5):512-6./[2]Al-Jaderi Z, et al. Effects of vitamin D3, calcipotriol and FTY720 on the expression of surface molecules and cytolytic activities of human natural killer cells and dendritic cells. Toxins (Basel). 2013 Oct 28;5(11):1932-47./[3]Pommergaard HC, et al. Combination chemoprevention with diclofenac, calcipotriol and difluoromethylornithine inhibits development of non-melanoma skin cancer in mice. Anticancer Res. 2013 Aug;33(8):3033-9./[4]Reinhard Bredehorst, et al. Induction of Antigen-Specific Tolerance by Peripheral Phagocytosis. US 20150283231 A1./[5]Kaur A, et al. Nanoemulsion loaded gel for topical co-delivery of clobitasol propionate and calcipotriol in psoriasis. Nanomedicine. 2017 May;13(4):1473-1482.
CAS Number: 112965-21-6
Molecular Weight: 412.60
Compound Purity: 99.73
Research Area: Inflammation/Immunology; Cancer
Target: Reference Standards;VD/VDR
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