Target Synonym: Carboxypeptidase A;procarboxypeptidase A;Carboxypeptidase A2;carboxypeptidase A2 (pancreatic);CPA 2;pancreatic;procarboxypeptidase A2;CPA2
Background: Carboxypeptidase A2 ( CPA2 ) is a secreted pancreatic procarboxy -peptidase, and cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group. The hydrolytic action of CPA2 was identified with a preference towards long substrates with aromatic amino acids in their C-terminal end, particularly tryptophan. CPA2 comprises a signal peptide, a pro region and a mature chain, and can be activated after cleavage of the pro peptide. Three different forms of human pancreatic procarboxypeptidase A have been isolated, and the A1 and A2 forms are always secreted as monomeric proteins with different biochemical properties.
Immunogen: Recombinant Human Carboxypeptidase A2/CPA2 protein
Buffer: 0.2 μm filtered solution in PBS
Dilution: IHC-P 1:50-1:200
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