CCT007093, CAS 176957-55-4

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 2E,5E-bis(2-thienylmethylene)-cyclopentanone

Purity: ≥98%

Formula Markup: C15H12OS2

Formula Weight: 272.4

CAS Number: 176957-55-4

Notes: CCT007093 is an inhibitor of protein phosphatase 1D (PPM1D, also known as PP2Cδ and WIP1; IC50 = 8.4 µM), which is encoded by a putative oncogene that is amplified in multiple cancer types.{32263} It does not inhibit PPM1A. CCT007093 selectively inhibits the growth of cancer cells that overexpress PPM1D, including MCF-7, KPL-1, and MCF-3B cells, as well as certain ovarian clear cell carcinoma cells.{32263,32264} CCT007093 has been used to elucidate the mechanism by which PPM1D drives growth in medulloblastoma cells.{32262}

• Artikelnummer: CAY19992-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 19992-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK