Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 4-(6-hydroxy-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)-benzoic acid
Purity: ≥98%
Formula Markup: C27H26O3
Formula Weight: 398.5
CAS Number: 107430-66-0
Notes: CD1530 is a selective retinoic acid receptor (RARγ) agonist (Kds = 150, 1,500, and 2,750 nM for RARγ, RARβ, and RARα receptors, respectively).{24736} It demonstrates transcriptional activity at RARγ with an AC50 value of 1.8 nM.{24736} It has been used in combination with bexarotene (Item No. 11571), a retinoid X receptor agonist, to inhibit oral carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide in a mouse model of human oral-cavity and esophageal squamous-cell carcinoma.{31184}