CD1530, CAS 107430-66-0

CD1530, CAS 107430-66-0
Artikelnummer
CAY19062-5
Verpackungseinheit
5 mg
Hersteller
Cayman Chemical

Verfügbarkeit: wird geladen...
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Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 4-(6-hydroxy-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)-benzoic acid

Purity: ≥98%

Formula Markup: C27H26O3

Formula Weight: 398.5

CAS Number: 107430-66-0

Notes: CD1530 is a selective retinoic acid receptor (RARγ) agonist (Kds = 150, 1,500, and 2,750 nM for RARγ, RARβ, and RARα receptors, respectively).{24736} It demonstrates transcriptional activity at RARγ with an AC50 value of 1.8 nM.{24736} It has been used in combination with bexarotene (Item No. 11571), a retinoid X receptor agonist, to inhibit oral carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide in a mouse model of human oral-cavity and esophageal squamous-cell carcinoma.{31184}
Mehr Informationen
Artikelnummer CAY19062-5
Hersteller Cayman Chemical
Hersteller Artikelnummer 19062-5
Verpackungseinheit 5 mg
Mengeneinheit STK
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