CD1530, CAS 107430-66-0

Product Description: CD1530 is a selective RARγ agonist with an Kd of 150 nM[1]. CD1530 has been used in combination with bexarotene to inhibit oral carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide in a mouse model of human oral-cavity and esophageal squamous-cell carcinoma[2].

Applications: Cancer-programmed cell death

Formula: C27H26O3

References: [1]Bernard BA, et al. Identification of synthetic retinoids with selectivity for human nuclear retinoic acid receptor gamma. Biochem Biophys Res Commun. 1992 Jul 31;186(2):977-83./[2]Tang XH, et al. Combination of bexarotene and the retinoid CD1530 reduces murine oral-cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide. Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8907-12.

CAS Number: 107430-66-0

Molecular Weight: 398.49

Compound Purity: 98.13

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: RAR/RXR

• Artikelnummer: MEXHY-108527-25
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-108527-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK