Description: CD3 chains. CD3 plays a critical role in TCR signal transduction, T-cell activation, and antigen recognition by binding the peptide/MHC antigen complex. The 145-2C11 antibody is useful for in vitro blocking and activation assays, as well as apoptosis induction and in vivo T-cell depletion.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Origin: Animal - Armenian Hamster, Bos taurus (bovine)
Conjugate: CF740
Concentration: 0.1 mg/mL
Storage buffer: PBS, 0.1% rBSA, 0.05% azide
Clone: 145-2C11
Immunogen: H2Kb specific Mouse cytotoxic T lymphocyte clone BM10 37
Antibody Reactivity: CD3e
References: Note: References for this clone sold by other suppliers may be listed for expected applications.
- PNAS USA (1987) 84:1374-1378. (Flow, IP)
- Eur J Immunol (1990) 20: 509-515. (functional studies)
- J Immunol (2003) 171:2496-2503. (Flow; IP; functional studies)
Entrez Gene ID: 12501
Expected AB Applications: Flow, surface (published for clone)/Functional studies (published for clone)/IP (published for clone)
Z-Antibody Applications: Flow, surface (published)/Functional studies (published)/IP (published)
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