Clone Name: 10A2
Application Note: IHC-Fr: 1:20 - 1:100. FCM: 1:20 - 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: 500 μg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010]
Uniprot ID: P01730
Antigen Species: Human
Immunogen: Human recombinant CD4 extracellular domain
Purification: Protein G purified
Conjugation: Unconjugated
Full Name: CD4 molecule