Clone Name: HL3636
Light Chain: Kappa
Application Note: WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Specificity/Sensitivity: This antibody was raised against human CD74 Intracellular domain.
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Uniprot ID: P04233
Antigen Species: Human
Immunogen: Synthetic peptide encompassing a sequence within the Intracellular domain of human CD74. The exact sequence is proprietary.
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
Full Name: CD74 molecule
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