Product Description: Cdc7-IN-1 (Compound 13) is a highly potent, selective and ATP competitive inhibitor of Cdc7 kinase, with an IC50 value of 0.6 nM at 1 mM ATP and with slow off-rate characteristics. Cdc7-IN-1 potently inhibits Cdc7 activity in cancer cells, and effectively induces cell death[1].
Applications: Cancer-Kinase/protease
Formula: C21H16ClN3O4
References: [1]Irie T, et al. Discovery of novel furanone derivatives as potent Cdc7 kinase inhibitors. Eur J Med Chem. 2017 Apr 21;130:406-418.
CAS Number: 1402055-25-7
Molecular Weight: 409.82
Compound Purity: 99.77
Research Area: Cancer
Solubility: DMSO : 5.2 mg/mL (ultrasonic)
Target: CDK