CDDO Borate Prodrug 4, CAS 2763063-09-6

Shelf life (days): 1460

Info: An anticancer agent and a prodrug form of a CDDO derivative; converted to the CDDO derivative by ROS; selectively inhibits the proliferation of BGC-823 cells in the presence of H2O2 over GES-1 cells (IC50s = 1.2 and 4.8 µM, respectively); does not affect the GSSG to GSH ratio, indicating a low toxicity risk, in BGC-823 cells when used at a concentration five-fold higher than the active metabolite; induces tumor regression and does not decrease body weight or induce organ toxicity in a BGC-823 mouse xenograft model at 5 mg/kg

Formulation: A solid

Formal Name: 2-cyano-3,12-dioxo-oleana-1,9(11)-dien-28-oic acid, 4-[[4-[[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methoxy]benzoyl]oxy]butyl ester

Purity: ≥95%

Formula Markup: C55H70BNO9

Formula Weight: 899.973

CAS Number: 2763063-09-6

• Artikelnummer: CAY42718-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 42718-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK