Clone Name: CEA31
Light Chain: Kappa
Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Positive Control: Colon carcinoma
Specificity/Sensitivity: Clone CEA31 has a high affinity for CEA and shows no detectable reactivity to nonspecific cross-reacting antigen (NCA), biliary glycoprotein (BGP) and human polymorphonuclear leucocytes.
Form: Liquid
Buffer (with preservative): Tris-HCl, 0.2% BSA, 0.09% Sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
Uniprot ID: P06731
Antigen Species: Human
Immunogen: Human colon carcinoma extract
Purification: Purified IgG
Conjugation: Unconjugated
Full Name: carcinoembryonic antigen related cell adhesion molecule 5
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