Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-pyridinium, pentahydrate
Purity: ≥95%
Formula Markup: C22H22N6O7S2 / 5H2O
Formula Weight: 636.7
CAS Number: 78439-06-2
Notes: Ceftazidime is a cephalosporin antibiotic.{58320} It is active against isolates of numerous Gram-positive and Gram-negative bacteria, including E. coli, K. pneumoniae, P. mirabilis, and S. pyogenes (MICs = 0.015-8 µg/ml for all). It binds to E. coli penicillin-binding protein 1a (PBP1a), -1b, -2, and -3 (IC50s = 0.9, 3.4, 240, and 0.06 µg/ml, respectively).{57920} Ceftazidime increases survival in mice infected with strains of S. aureus, E. coli, K. pneumoniae, Proteus, or Serratia (ED50s = 0.1-25 mg/kg for all).{58320} Formulations containing ceftazidime have been used in the treatment of bacterial infections.
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