Target Synonym: CGGBP1;CGGBP;p20-CGGBP
Storage: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Background: This gene encodes a CGG repeat-binding protein that primarily localizes to the nucleus. CGG trinucleotide repeats are implicated in many disorders as they often act as transcription- and translation-regulatory elements, can produce hairpin structures which cause DNA replication errors, and form regions prone to chromosomal breakage. CGG repeats are also targets for CpG methylation. In addition to its ability to bind CGG repeats and regulate transcription, this gene is believed to play a role in DNA damage repair and telomere protection. In vitro studies indicate this protein does not bind to methylated CpG sequences.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Immunogen: Recombinant fusion protein of human CGGBP1 (NP_003654.3).
Dilution: WB 1:500-1:2000
Calculated MW: 18kDa
Observed MW: 20kDa
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