Product Description: CGP 44 645 is the methanol metabolite of Letrozole (HY-14248) and is a molecular indicator for evaluating its metabolic kinetics in microsomes in vitro. Levels of CGP 44 645 in rat liver microsomes may be sex-specific[1].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C15H10N2O
References: [1]Tao X, Piao H, Canney DJ, Borenstein MR, Nnane IP. Biotransformation of letrozole in rat liver microsomes: effects of gender and tamoxifen. J Pharm Biomed Anal. 2007 Feb 19;43(3):1078-85.
CAS Number: 134521-16-7
Molecular Weight: 234.258
Compound Purity: 98.13
Research Area: Others
Solubility: DMSO : ≥ 200 mg/mL
Target: Drug Metabolite