CGP 71683 (hydrochloride), CAS 192322-50-2

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N-[[trans-4-[[(4-amino-2-quinazolinyl)amino]methyl]cyclohexyl]methyl]-1-naphthalenesulfonamide, monohydrochloride

Purity: ≥98%

Formula Markup: C26H29N5O2S / HCl

Formula Weight: 512.0676

CAS Number: 192322-50-2

Notes: CGP 71683 is an antagonist of neuropeptide Y (NPY) receptor Y5 (IC50 = 1.4 nM in a radioligand binding assay).{52105} It is selective for Y5 over Y1, Y2, and Y4 receptors (IC50s = 2,765, 7,187, and 5,637 nM, respectively). It inhibits NPY-induced increases in BT-549 cell growth and MDA-MB-231 cell migration when used at a concentration of 0.25 μM.{52104} CGP 71683 (10 mg/kg, i.p.) inhibits increases in food intake induced by intracerebroventricular administration of NPY in rats.{52105}

• Artikelnummer: CAY28778-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 28778-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK