Product Description: Choline bitartrate is a vitamin-like essential nutrient, can affect diseases such as liver disease, atherosclerosis and neurological disorders[1][2]. Choline bitartrate is a precursor for the neurotransmitter acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism[3].
Applications: Neuroscience-Neuromodulation
Formula: C9H19NO7
References: [1]Hollenbeck CB, et al. An introduction to the nutrition and metabolism of choline. Cent Nerv Syst Agents Med Chem. 2012 Jun;12(2):100-13./[2]Corbin KD, et al. Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression. Curr Opin Gastroenterol. 2012 Mar;28(2):159-65./[3]Shinobu Kuwae, et al. Development of a chemically defined platform fed-batch culture media for monoclonal antibody-producing CHO cell lines with optimized choline content. Cytotechnology. 2018 Jun;70(3):939-948./[4]Rebecca C Schugar, et al. Role of choline deficiency in the Fatty liver phenotype of mice fed a low protein, very low carbohydrate ketogenic diet. PLoS One. 2013 Aug 29;8(8):e74806.
CAS Number: 87-67-2
Molecular Weight: 253.25
Compound Purity: 98.0
Research Area: Neurological Disease; Cancer
Solubility: DMSO : 55 mg/mL (ultrasonic)/H2O : 120 mg/mL (ultrasonic)
Target: Endogenous Metabolite;mAChR