Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: (3-chlorophenyl)[3,4-dihydro-6,7-dimethoxy-1-[(4-methoxyphenoxy)methyl]-2(1H)-isoquinolinyl]-methanone
Purity: ≥98%
Formula Markup: C26H26ClNO5
Formula Weight: 467.9
CAS Number: 486427-17-2
Notes: CIQ is a substituted tetrahydroisoquinoline that acts as a subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors.{32554} It is without effect at subunits NR2A, NR2B, or glutamate receptors. CIQ enhances receptor responses two-fold (EC50 = 3 µM) by increasing channel opening frequency for glutamate or glycine.{32554} It is a positive allosteric modulator that does not alter agonist EC50 values.{32553,32552}