Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 4-[3-[(3Z)-2-(trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol, dihydrochloride
Purity: ≥95%
Formula Markup: C23H25F3N2OS / 2HCl
Formula Weight: 507.4
CAS Number: 51529-01-2
Notes: cis-Flupenthixol is a typical antipsychotic, a dopamine D2 receptor antagonist (Ki = 0.38 nM), and an inverse agonist at the serotonin (5-HT) receptor subtype 5-HT2A (Ki = 7 nM).{26444} In vivo, cis-flupenthixol (0.5 mg/kg, i.p.) reduces cocaine-induced locomotor activity and prevents development of conditioned place preferences for the immediate effects of intravenously administered cocaine without affecting development of conditioned place aversions in rats.{42313} cis-Flupenthixol also inhibits acid sphingomyelinase activity by 81.8% when used at a concentration of 10 mM.{26583}