Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: P'-[2-(trimethylammonio)ethyl] ester-cytidine 5'-(trihydrogen diphosphate)-inner, monosodium salt
Purity: ≥95%
Formula Markup: C14H25N4O11P2 / Na
Formula Weight: 510.305952
CAS Number: 33818-15-4
Notes: Citicoline is an endogenous intermediate in the synthesis of phosphatidylcholine, the major phospholipid in eukaryotic cells.{23421} It also serves as a choline donor in the biosynthesis of the neurotransmitter acetylcholine. Citicholine demonstrates protective effects in cerebral ischemia, traumatic brain injury, and memory disorders.{23420} Exogenous administration of citicholine to rodents (500 mg/kg i.p. immediately after ischemia and at 3-h reperfusion) has been shown to stimulate the synthesis of phosphatidylcholine, sphingomyelin, and cardiolipin and to attenuate the release of arachidonic acid and the accumulation of ceramide.{23419}
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