Shelf life (days): 730.0
Formulation: A solid
Formal Name: (E)-N,5-bis(4-chlorophenyl)-3-((propan-2-yl-d7)imino)-3,5-dihydrophenazin-2-amine
Purity: ≥99% deuterated forms (d1-d7)
Formula Markup: C27H15Cl2D7N4
Formula Weight: 480.43836
Notes: Clofazimine-d7 is intended for use as an internal standard for the quantification of clofazimine (Item No. 23301) by GC- or LC-MS. Clofazimine is an antimycobacterial compound with MICs ranging from 0.03 to 0.12 μg/ml against clinical isolates of M. paratuberculosis.{36183} It also has activity against 80 isolates of M. fortuitum, M. chelonae, and M. fallax (MICs = ≤0.25-8 μg/ml).{36184} Clofazimine (25 mg/kg per day) reduces the number of M. tuberculosis-infected cells in the spleen and lungs of mice infected with the multidrug-resistant clinical isolate strain CNL.{36185} Formulations containing clofazimine have been used for the treatment of leprosy and drug-resistant tuberculosis.{36186}
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