Product Description: CM010 is a potent and selective aldehyde dehydrogenase 1A (ALDH1A) family inhibitor, with IC50s of 1700, 740, and 640 nM for ALDH1A1, ALDH1A2, and ALDH1A3, respectively. CM010 does not inhibit any of the other ALDH family members. CM010 can regulate metabolism and has anti-cancer activity[1].
Applications: Cancer-programmed cell death
Formula: C20H23N3O
References: [1]Chefetz I, et al. A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells. Cell Rep. 2019 Mar 12;26(11):3061-3075.e6.
CAS Number: 692269-09-3
Molecular Weight: 321.42
Compound Purity: 98.07
Research Area: Cancer; Metabolic Disease
Solubility: DMSO : 125 mg/mL (ultrasonic)
Target: Aldehyde Dehydrogenase (ALDH)