Shelf life (days): 1460.0
Formulation: A solid
Formal Name: (aE,1'R,6'S,7'S,8'aS)-6'-ethyl-1,2,2',3',6',7',8',8'a-octahydro-a-(methoxymethylene)-2-oxo-spiro[3H-indole-3,1'(5'H)-indolizine]-7'-acetic acid, methyl ester
Purity: ≥95%
Formula Markup: C22H28N2O4
Formula Weight: 384.4688
CAS Number: 17391-18-3
Notes: An oxindole alkaloid with diverse biological activities; induces autophagy in Drosophila second instar larvae at 100 µM; inhibits apomorphine- and methamphetamine-induced hyperlocomotion in mice at 100 mg/kg; increases the duration of thiopental-induced sleep in mice at 100 mg/kg; increases the length of freezing time induced by footshock in a contextual fear conditioning test, decreases the latency to escape in the Morris water maze, and increases the number of hippocampal synaptic connections in the 5XFAD transgenic mouse model of Alzheimer's disease in exosomes
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