Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 2-[3-(2,4-difluorophenyl)-4,5-dihydro-5-isoxazolyl]-1-(4-morpholinyl)-ethanone
Purity: ≥95%
Formula Markup: C15H16F2N2O3
Formula Weight: 310.296026
CAS Number: 1309793-47-2
Notes: CPSI-1306 is an inhibitor of macrophage inhibitory factor (MIF).{53398,53399} In vivo, CPSI-1306 (20 mg/kg per day) decreases skin thickness and myeloperoxidase (MPO) activity and induces keratinocyte apoptosis, as well as reduces papilloma formation and progression to micro-invasive squamous cell carcinoma (SCC) in a mouse model of UVB-induced SCC.{53398} It lowers blood glucose levels and serum levels of IL-6 and TNF-α in a mouse model of non-insulin-dependent diabetes mellitus (NIDDM) induced by streptozotocin (Item No. 13104).{53399}