CPYPP, CAS 310460-39-0

Product Description: CPYPP is a DOCK2-Rac1 interaction inhibitor. CPYPP binds to DOCK2 DHR-2 domain and inhibits the guanine nucleotide exchange factor (GEF) activity of DOCK2DHR-2 for Rac1 in a dose-dependent manner with an IC50 of 22.8 μM. CPYPP also inhibits DOCK180 and DOCK5 and less inhibits DOCK9[1].

Applications: COVID-19-immunoregulation

Formula: C18H13ClN2O2

References: [1]Nishikimi A, et al. Blockade of inflammatory responses by a small-molecule inhibitor of the Rac activator DOCK2. Chem Biol. 2012 Apr 20;19(4):488-97.

CAS Number: 310460-39-0

Molecular Weight: 324.76

Compound Purity: 99.94

Research Area: Inflammation/Immunology

Solubility: DMSO : 25 mg/mL (ultrasonic)

Target: DOCK

• Artikelnummer: MEXHY-110100-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-110100-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK