CTS-1027, CAS 193022-04-7

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 4-[[[4-(4-chlorophenoxy)phenyl]sulfonyl]methyl]tetrahydro-N-hydroxy-2H-pyran-4-carboxamide

Purity: ≥98%

Formula Markup: C19H20ClNO6S

Formula Weight: 425.88394

CAS Number: 193022-04-7

Notes: CTS-1027 is an inhibitor of matrix metalloproteinases (MMPs).{67181} It is selective for MMP-2, MMP-9, and MMP-13 (Kis= 0.22, 0.55, and 0.52 nM, respectively) over MMP-3 and MMP-1 (Kis= 9.3 and 590 nM, respectively). CTS-1027 (10 mg/kg) reduces hepatocyte apoptosis and bile infarcts and increases survival in a mouse model of bile duct ligation-induced cholestatic liver injury.{67180}

• Artikelnummer: CAY33219-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 33219-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: Reinstoffe