CUDC-907, CAS 1339928-25-4

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: N-hydroxy-2-[[[2-(6-methoxy-3-pyridinyl)-4-(4-morpholinyl)thieno[3,2-d]pyrimidin-6-yl]methyl]methylamino]-5-pyrimidinecarboxamide

Purity: ≥98%

Formula Markup: C23H24N8O4S

Formula Weight: 508.55418

CAS Number: 1339928-25-4

Notes: CUDC-907 is a dual inhibitor of HDACs and phosphatidylinositol 3-kinases (PI3Ks).{47027} It inhibits HDAC activity in HeLa nuclear extracts (IC50 = 50s = 50s = 2/M phase and apoptosis and decreases cellular migration and invasion in FTC-133, THJ-29T, XTC-1, and 8505C thyroid cancer cell lines in a concentration-dependent manner.{47026} CUDC-907 (75 mg/kg) reduces tumor growth, the number of liver metastases, and HDAC2 expression in tumor tissue in the FTC-133 mouse xenograft model.

• Artikelnummer: CAY25651-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 25651-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK