Cyclopiazonic Acid, CAS 18172-33-3

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 10-acetyl-2,6,6aR,7,11aS,11bR-hexahydro-11-hydroxy-7,7-dimethyl-9H-pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indol-9-one

Purity: ≥95%

Formula Markup: C20H20N2O3

Formula Weight: 336.4

CAS Number: 18172-33-3

Notes: Cyclopiazonic acid is a mycotoxin that has been found in Penicillium and Aspergillus and an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+-ATPase (SERCA; IC50 = 0.6 µM).{20510,20511} In vivo, cyclopiazonic acid (11-14 mg/kg) induces ptosis, hypothermia, tremor, and cachexia, as well as induces lethality (LD50 = 13 mg/kg), in rats.{61119} It induces tachycardia and sedation in rabbits when administered at a dose of 10 mg/kg.

• Artikelnummer: CAY11326-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 11326-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK