Cysteamine-d4 (hydrochloride), CAS 1219805-04-5

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 2-amino-ethanethiol-d4, monohydrochloride

Purity: ≥99% deuterated forms (d1-d4)

Formula Markup: C2H3D4NS / HCl

Formula Weight: 117.6346

CAS Number: 1219805-04-5

Notes: Cysteamine-d4 is intended for use as an internal standard for the quantification of cysteamine (hydrochloride) (Item No. 22193) by GC- or LC-MS. Cysteamine is a stable aminothiol with radioprotective activities.{41003} It reduces ionizing radiation-induced death and chromosomal damage in mice in a dose-dependent manner.{41003,41004} Cysteamine binds rapidly and temporarily to plasma proteins upon administration and this activity is directly correlated to its radioprotective effects.{41004} In vitro, 0.1 mM cysteamine depletes 90% of free cystine from cystinotic fibroblasts.{41005} Formulations containing cysteamine have been used to treat nephropathic cystinosis and reduce glomerular deterioration in humans.

• Artikelnummer: CAY33297-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 33297-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung