Cytokeratin 6A (KRT6A) (Basal Cell Marker) (KRT6A/2368), CF740 conjugate, 0.1mg/mL

Cytokeratin 6A (KRT6A) (Basal Cell Marker) (KRT6A/2368), CF740 conjugate, 0.1mg/mL
Artikelnummer
BTMBNC742368-500
Verpackungseinheit
500 uL
Hersteller
Biotium

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Description: This MAb recognizes a protein of 56 kDa, identified as cytokeratin 6A (KRT6A). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns. Cytokeratin 6A is the dominant form in epithelial tissue. Cytokeratin 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Cytokeratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express KRT6 and KRT16. KRT6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Origin: Animal - Mus musculus (mouse), Bos taurus (bovine)

Conjugate: CF740

Concentration: 0.1 mg/mL

Storage buffer: PBS, 0.1% rBSA, 0.05% azide

Clone: KRT6A/2368

Immunogen: Recombinant full-length human Cytokeratin 6A (KRT6A) protein

Antibody Reactivity: Cytokeratin 6A

Entrez Gene ID: 3853

Z-Antibody Applications: Flow, intracellular (verified)/IHC, FFPE (verified)

Verified AB Applications: Flow (intracellular) (verified)/IHC (FFPE) (verified)

Antibody Application Notes: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody/Immunohistology (formalin): 1-2 ug/mL for 30 minutes at RT/Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes/Optimal dilution for a specific application should be determined by user
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Artikelnummer BTMBNC742368-500
Hersteller Biotium
Hersteller Artikelnummer BNC742368-500
Verpackungseinheit 500 uL
Mengeneinheit STK
Reaktivität Human
Klonalität Monoclonal
Methode Flow Cytometry, Immunohistochemistry
Isotyp IgG2a kappa
Wirt Mouse
Konjugat Conjugated, CF740
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