Dabigatran-d3, CAS 1246817-44-6

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 3-(2-(((4-carbamimidoylphenyl)amino)methyl)-1-(methyl-d3)-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoic acid

Purity: ≥99% deuterated forms (d1-d3)

Formula Markup: C25H22D3N7O3

Formula Weight: 474.52956

CAS Number: 1246817-44-6

Notes: Dabigatran-d3 is intended for use as an internal standard for the quantification of dabigatran (Item No. 17133) by GC- or LC-MS. Dabigatran is an inhibitor of thrombin (Ki = 0.0045 µM) and an active metabolite of the thrombin inhibitor prodrug dabigatran etexilate (Item No. 17131).{28063,28064} It also inhibits trypsin (Ki = 0.0503 µM) but is selective for thrombin and trypsin over plasmin, Factor Xa, activated protein C, and tissue plasminogen activator (tPA; Kis = 1.695, 3.76, 20.93, and 45.36 µM, respectively).{28063}

• Artikelnummer: CAY35704
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 35704-500
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung