Product Description: Danofloxacin mesylate (Standard) is the analytical standard of Danofloxacin mesylate. This product is intended for research and analytical applications. Danofloxacin mesylate (CP 76136-27) is a fluoroquinolone used as a veterinary drug. Danofloxacin mesylate has a broad spectrum of bactericidal activity, mainly inhibiting the DNA cycloenzyme of the bacteria. In addition, Danofloxacin mesylate is a substrate for ATP-dependent efflux transporters (P-gp and MRP2)[1][2].
Formula: C20H24FN3O6S
References: [1]Giles, C.J., et al., Clinical pharmacokinetics of parenterally administered danofloxacin in cattle. J Vet Pharmacol Ther, 1991. 14(4): p. 400-10./[2]McGuirk, P.R., et al., Synthesis and structure-activity relationships of 7-diazabicycloalkylquinolones, including danofloxacin, a new quinolone antibacterial agent for veterinary medicine. J Med Chem, 1992. 35(4): p. 611-20.
CAS Number: 119478-55-6
Molecular Weight: 453.48
Research Area: Infection
Target: Antibiotic;Bacterial;Reference Standards
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