Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 5-(dimethylamino)-1-naphthalenesulfonamide
Purity: ≥98%
Formula Markup: C12H14N2O2S
Formula Weight: 250.31784
CAS Number: 1431-39-6
Notes: Dansyl amide is a fluorescent probe for albumin and CAII.{65104,65105} It binds to serum albumin and carbonic anhydrase II (CAII; Kds = 7.57 and 0.2 µM, respectively) and has been used to determine ligand affinities for these proteins. Dansyl amide binding to CAII results in an increase in fluorescence due to FRET from nearby active site tryptophan residues and displays excitation/emission maxima of 280/470 nm, respectively, when bound to CAII and a decrease in fluorescence can be used to quantify CAII ligand binding.{65105}