Datopotamab Deruxtecan, CAS 2238831-60-0

Datopotamab Deruxtecan, CAS 2238831-60-0
Artikelnummer
BPS82921-2
Verpackungseinheit
5 mg
Hersteller
BPS Bioscience

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Background: Trophoblast cell-surface antigen 2 (TROP-2, also known as tumor associated calcium signal transducer 2, TACSTD2, GA733-1 or M1S1), is a cell surface glycoprotein that is highly expressed in a variety of solid cancers compared to normal cells. Through a variety of signaling pathways, TROP2 regulates cancer growth and metastasis and is a candidate target for antibody drug conjugates (ADC) and immunotherapy.

CAS Number: 2238831-60-0

Description: Datopotamab deruxtecan (DS-1062; Dato-DXd) is a trophoblast cell surface antigen 2 (TROP2)-directed antibody-drug conjugate (ADC). Datopotamab deruxtecan has a potent antitumor activity.1

Format: Aqueous buffer solution.

Purity: ≥90%

Storage Stability: Store at -80°C, protect from light.

Target: TROP2

Uniprot: P09758

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

References: 1. Daisuke Okajima, et al., 2021 Mol Cancer Ther. 20(12):2329-2340.
Mehr Informationen
Artikelnummer BPS82921-2
Hersteller BPS Bioscience
Hersteller Artikelnummer 82921-2
Verpackungseinheit 5 mg
Mengeneinheit STK
Klonalität Monoclonal
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