Product Description: dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP based on Cereblon ligand. dCBP-1 is exceptionally potent at killing multiple myeloma cells and ablates oncogenic enhancer activity driving MYC expression[1].
Applications: Cancer-programmed cell death
Formula: C51H63F2N11O10
References: [1]Raghu Vannam, et al. Targeted degradation of the enhancer lysine acetyltransferases CBP and p300. Cell Chem Biol. 2020 Dec 31;S2451-9456(20)30513-4.
CAS Number: 2484739-25-3
Molecular Weight: 1028.11
Compound Purity: 99.44
Research Area: Cancer
Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 80°C)