Product Description: Dechloro Rivaroxaban is a highly selective, orally active inhibitor of Factor Xa. Dechloro Rivaroxaban inhibits human free FXa with a Ki of 0.4 nM. Dechloro Rivaroxaban inhibits prothrombinase activity and fibrin-associated FXa activity with IC50s of 2.1 nM and 92 nM, respectively[1].
Applications: Neuroscience-Neuromodulation
Formula: C19H19N3O5S
References: [1]Lang D, et al. In vitro metabolism of rivaroxaban, an oral, direct factor Xa inhibitor, in liver microsomes and hepatocytes of rats, dogs, and humans. Drug Metab Dispos. 2009 May;37(5):1046-55.
CAS Number: 1415566-28-7
Molecular Weight: 401.44
Compound Purity: 99.94
Research Area: Cardiovascular Disease
Solubility: DMSO : 50 mg/mL (ultrasonic)
Target: Factor Xa