Shelf life (days): 1460.0
Formulation: A solid
Formal Name: (7S)-7,8-dihydro-7-hydroxy-8,8-dimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-2-one
Purity: ≥98%
Formula Markup: C14H14O4
Formula Weight: 246.25856
CAS Number: 23458-02-8
Notes: Decursinol is a coumarin that has been found in Angelica gigas and has diverse biological activities.{60751,60752,60753,60754} It inhibits glutamate-induced neuronal cell death in primary rat mixed cortical cells when used at concentrations of 0.1, 1, and 10 µM. Dietary administration of decursinol (0.004%) reduces decreases in spontaneous alternation induced by amyloid-β (1-42) (Aβ42; Item No. 20574) in the Y-maze, indicating prevention of memory deficits, in mice.{60752} Decursinol (10 mg/kg) reduces tumor metastasis in a CT26 colorectal cancer mouse xenograft model.{60753} It inhibits acetic acid-induced writhing in mice when administered at a dose of 50 mg/kg.{60754}
Deutsch
English
