Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 2,6-dimethyl-4-(2-nitrophenyl)-3,5-dimethyl ester 3,5-pyridinedicarboxylic acid
Purity: ≥98%
Formula Markup: C17H16N2O6
Formula Weight: 344.3
CAS Number: 67035-22-7
Notes: Dehydro nifedipine is an active metabolite of nifedipine (Item No. 11106), a calcium channel blocker present in formulations used to treat hypertension and angina.{39341,39342,20226,20230} Dehydro nifedipine is formed when nifedipine is metabolized by the cytochrome P450 (CYP) isomers CYP3A4 and CYP3A5.{39342} Dehydro nifedipine inhibits glucose uptake in PC-12 cells with an IC50 value of 130 μM.{39341}