Demeclocycline, CAS 127-33-3

Demeclocycline, CAS 127-33-3
Artikelnummer
MEXHY-121268-10.1
Verpackungseinheit
10 mM/1 ml
Hersteller
MedChemExpress

Verfügbarkeit: wird geladen...
Preis wird geladen...
Product Description: Demeclocycline is an orally active tetracycline antibiotic. Demeclocycline impairs protein synthesis by binding to the 30S ribosomal subunit to inhibit binding of aminoacyl tRNA. Demeclocycline shows anti-bacterial activitise to a wide variety of bacterial infections[1][2].

Applications: COVID-19-immunoregulation

Formula: C21H21ClN2O8

Citations: J Photoch Photobio A. 2020 May. /Chemosphere. 2019 Jun;225:378-387. /Mol Syst Biol. 2022 Sep;18(9):e11081./Patent. US20230014181.

References: [1]I Chopra, et al. Tetracyclines, molecular and clinical aspects. J Antimicrob Chemother. 1992 Mar;29(3):245-77./[2]D Schnappinger, et al. Tetracyclines: antibiotic action, uptake, and resistance mechanisms. Arch Microbiol. 1996 Jun;165(6):359-69./[3]Marleen L A Kortenoeven, et al. Demeclocycline attenuates hyponatremia by reducing aquaporin-2 expression in the renal inner medulla. Am J Physiol Renal Physiol. 2013 Dec 15;305(12):F1705-18./[4]Susobhan Sarkar, et al. Demeclocycline Reduces the Growth of Human Brain Tumor-Initiating Cells: Direct Activity and Through Monocytes. Front Immunol. 2020 Feb 21;11:272.

CAS Number: 127-33-3

Molecular Weight: 464.85

Compound Purity: 98.0

Research Area: Cancer; Infection; Inflammation/Immunology

Solubility: DMSO : 25 mg/mL (ultrasonic)/H2O : 40 mg/mL (ultrasonic)

Target: Antibiotic;Bacterial
Mehr Informationen
Artikelnummer MEXHY-121268-10.1
Hersteller MedChemExpress
Hersteller Artikelnummer HY-121268-10.1
Verpackungseinheit 10 mM/1 ml
Mengeneinheit STK
Produktinformation (PDF) Download
MSDS (PDF) Download