Denfivontinib, CAS 1457983-28-6

Product Description: Denfivontinib (G-749) is a potent, oral active and ATP competitive FLT3 inhibitor, with IC50s of 0.4 nM and 0.6 nM for FLT3 wild type and FLT3-D835Y, respectively. Denfivontinib can be used for the research of agent resistance for acute myeloid leukemia (AML)[1].

Applications: Cancer-Kinase/protease

Formula: C25H25BrN6O2

References: [1]Lee HK, et al. G-749, a novel FLT3 kinase inhibitor, can overcome drug resistance for the treatment of acute myeloid leukemia. Blood. 2014 Apr 3;123(14):2209-19.

CAS Number: 1457983-28-6

Molecular Weight: 521.41

Compound Purity: 98.0

Research Area: Cancer

Solubility: DMSO : 25 mg/mL (ultrasonic)

Target: Apoptosis;FLT3

• Artikelnummer: MEXHY-12333-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-12333-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK