Product Description: ATX968 (example 31) is an inhibitor of ATP-dependent RNA helicase A (DHX9), with the EC50 of 0.054 μM in circBRIP1. ATX968 has antitumor activity[1].
Applications: Cancer-programmed cell death
Formula: C18H16ClN3O3S2
References: [1]DANIELS Matthew H., et al. Preparation of imidazopyridines, thienopyrimidines, pyrrolopyrimidines and related heterocycles as inhibitors of RNA helicase DHX9 useful in treatment of cancers. World Intellectual Property Organization, WO2023154519 A1 2023-08-17
CAS Number: 2973395-71-8
Molecular Weight: 421.92
Compound Purity: 98.83
Research Area: cancer
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: DNA/RNA Synthesis