Dihydroergocristine (mesylate), CAS 24730-10-7

Product Description: Dihydroergocristine mesylate (DHEC mesylate) is a inhibitor of γ-secretase (GSI), reduces the production of the Alzheimer's disease amyloid-β peptides, binds directly to γ-secretase and Nicastrin with equilibrium dissociation constants (Kd) of 25.7 nM and 9.8 μM, respectively[1].

Applications: Neuroscience-Neurodegeneration

Formula: C36H45N5O8S

References: [1]Lei X, et al. The FDA-approved natural product dihydroergocristine reduces the production of the Alzheimer's disease amyloid-β peptides. Sci Rep. 2015 Nov 16;5:16541.

CAS Number: 24730-10-7

Molecular Weight: 707.84

Compound Purity: 99.86

Research Area: Neurological Disease

Solubility: DMSO : 50 mg/mL (ultrasonic)/H2O : < 0.1 mg/mL

Target: Amyloid-β

• Artikelnummer: MEXHY-N2319-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N2319-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK