Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 5-phosphono-norvaline
Purity: ≥95%
Formula Markup: C5H12NO5P
Formula Weight: 197.1
CAS Number: 76326-31-3
Notes: DL-AP5 is the racemic version of the selective N-methyl-D-aspartate (NMDA) receptor antagonist, D-AP5 (Item No. 14539).{22827} Whereas D-AP5 is the active (−)-stereoisomer that competitively inhibits the glutamate binding site of NMDA receptors (Kd = 1.4 μM), the (+)-isomer (L-AP5) demonstrates considerably less potent NMDA receptor antagonist activity.{22827} AP5 has been widely used to study the activity of NMDA receptors particularly in regard to researching synaptic plasticity, learning, and memory.{22826}