Target Synonym: DNM1L; DLP1; DRP1; DVLP; DYMPLE; EMPF; EMPF1; HDYNIV; dynamin 1 like
Storage: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Background: This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.
Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Immunogen: Recombinant fusion protein of human DNM1L
Dilution: IF 1:50-1:200
Calculated MW: 60kDa/78kDa/79kDa/80kDa/81kDa/82kDa/83kDa
Observed MW: Refer to figures
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