Application Note: WB: 0.03-0.1μg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 54
Positive Control: The peptide used to generate this antibody is available for purchase (GTX89527-PEP).
Specificity/Sensitivity: This antibody is expected to recognise isoforms 1, 2, 3, 4 and 5 (NP_000781.1; NP_001229815.1; NP_001229816.1; NP_001229817.1; NP_001229818.1 respectively).
Form: Liquid
Buffer (with preservative): TBS, 0.5% BSA, 0.02% Sodium azide.
Concentration: 0.50 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2011]
Uniprot ID: P20711
Antigen Species: Human
Immunogen: Peptide with sequence C-WEHIKELAADVL, from the C Terminus of the protein sequence according to NP_000781.1; NP_001229815.1; NP_001229816.1; NP_001229817.1; NP_001229818.1.
Purification: Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
Conjugation: Unconjugated
Full Name: dopa decarboxylase
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