Product Description: Dorsomorphin (Compound C) is a selective and ATP-competitive AMPK inhibitor (Ki=109 nM in the absence of AMP). Dorsomorphin (BML-275) selectively inhibits BMP type I receptors ALK2, ALK3, and ALK6. Dorsomorphin can reverse autophagy activation and anti-inflammatory effect of Urolithin A (HY-100599)[1][2].
Applications: Cancer-Kinase/protease
Formula: C24H25N5O
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CAS Number: 866405-64-3
Molecular Weight: 399.49
Compound Purity: 99.91
Research Area: Cancer
Solubility: DMSO : 25 mg/mL (ultrasonic;adjust pH to 3 with 1 M HCl)
Target: AMPK;Autophagy;Organoid;TGF-β Receptor
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