Shelf life (days): 1460.0
Formulation: A solid
Formal Name: N-[(1S,9S)-9-ethyl-5-fluoro-2,3,9,10,13,15-hexahydro-9-hydroxy-4-methyl-10,13-dioxo-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl]-2-hydroxy-acetamide
Purity: ≥95%
Formula Markup: C26H24FN3O6
Formula Weight: 493.5
CAS Number: 1599440-33-1
Notes: Dxd is a derivative of the DNA topoisomerase I inhibitor exatecan (Item No. 35452) and a starting material that has been used in the synthesis of antibody-drug conjugates (ADCs).{67024} It has been used in the synthesis of ADCs targeting HER2 with anticancer activity in vitro and in vivo.