(E/Z)-THZ1 (dihydrochloride), CAS 2095433-94-4

Product Description: (E/Z)-THZ1 dihydrochloride is a selective inhibitor of CDK7 with an IC50 of 3.2 nM. (E/Z)-THZ1 dihydrochloride has antiproliferative effect[1][2].

Applications: Cancer-Kinase/protease

Formula: C31H30Cl3N7O2

References: [1]Kwiatkowski N, et al. Targeting transcription regulation in cancer with a covalent CDK7 inhibitor. Nature. 2014;511(7511):616-620./[2]Nilson KA, et al. THZ1 Reveals Roles for Cdk7 in Co-transcriptional Capping and Pausing. Mol Cell. 2015;59(4):576-587.

CAS Number: 2095433-94-4

Molecular Weight: 638.97

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: CDK

• Artikelnummer: MEXHY-80013B-25
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-80013B-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK