Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 4-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)ethynyl]-benzoic acid
Purity: ≥98%
Formula Markup: C23H24O2
Formula Weight: 332.4
CAS Number: 104561-41-3
Notes: All-trans retinoic acid (ATRA, Item No. 11017) is frequently used in cell culture to induce stem cell differentiation or enhance the growth, differentiation, and maintenance of neural cell types.{27145,27146,27147} Unfortunately, ATRA is readily susceptible to isomerisation and degradation upon exposure to light or other factors such as temperature and oxidation, which presents confounding issues for cell culture. EC 23 is a photostable synthetic analog of ATRA that induces differentiation in human pluripotent embryonic stem cells when used within the range of 100 nM-10 µM.{27145,27146,27147}
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